Directions Apply a small amount to face in the PM as part of your skincare regimen, after water-based serums but before heavier treatments. Do not use with other retinoid treatments. Avoid unprotected solar exposure. Caution: Retinol can cause irritation, redness and peeling, especially around the eyes and mouth, in the early stages of treatment while skin builds tolerance. If persistent irritation occurs, cease use and consult a physician. Use only as directed on unbroken skin. Patch testing prior to use is advised. Refer to our in-depth guide to patch testing. Keep out of reach of children. Refrigerate after opening. This water-free solution contains 0.5% pure Retinol, an ingredient that can reduce the appearances of fine lines, of photo damage and of general skin aging. While Retinol has been studied extensively, it is irritating to the skin and newer technologies exist that mimic the visible effects of Retinol without causing skin irritation. For this reason, we generally recommend using Granactive Retinoid 2% or Granactive Retinoid 5% instead of this formula. Caution: Retinol can cause significant irritation, redness and peeling, especially around the eyes and mouth, in the early stages of treatment while skin builds tolerance. If you have not used high-strength retinol formulas in the past, we strongly recommend that you start your retinol regimen with our Retinol 0.2% in Squalane and adjust to higher strengths of Retinol 0.5% in Squalane and Retinol 1% in Squalane as your skin builds tolerance. You will achieve the same end results without the unpleasant redness and peeling along the way. Note: Water can affect the stability of retinol. Additionally, plant oils in retinol formulations can trigger lipid peroxidation and can impair r
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